http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021148564-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adb0e564374fedf34b36103d36e6455a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L17-145 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L17-14 |
| filingDate | 2021-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_234126bf7e52a0fa540ef081b6123e73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b877c80244eaa05868f2de5ed8d6e71d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_345d0979ea123028b3160708126f1c11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ce8a0bc7375bc00915843463c007506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1cfa4c2dba6a99c05e0a5ad926da989 |
| publicationDate | 2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021148564-A1 |
| titleOfInvention | Method of cross-linking biomaterial with a polyfunctional aziridine compound and products obtained therewith |
| abstract | The present invention relates to a method of cross-linking a natural or synthetic biopolymer with a polyfunctional aziridine cross-linking agent, like a method of making a coating comprising cross-linked biopolymer on a substrate. Such method can be performed at conditions compatible with natural biopolymers without inducing denaturation of proteins like collagens, and results in cross-linked materials having improved physical properties, good stability under physiological conditions, and suitable biocompatibility. The cross-linking method and/or the coating method may also be applied as a sequence of steps, like in an additive manufacturing or 3D-printing process to form an article. The invention also provides an article or a component comprising cross-linked biopolymer as can be obtained with said methods, like a porous material comprising a collagen-based sheet or other structure for use in for example tissue engineering. In other aspects a medical device or implant is provided, which comprises an article or a component comprising cross- linked biopolymer as can be obtained with the above methods, like an orthopedic implant having a collagen-based coating on at least part of its surface. |
| priorityDate | 2020-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 232.