| abstract |
The present invention relates to the field of microneedle-array transdermal drug delivery, specifically to a colchicine-containing soluble microneedle patch and a preparation method therefor. The microneedle patch comprises a hyaluronic acid microneedle array containing drug colchicine, a substrate, and a medical adhesive tape; the microneedles are conical or pyramidal in shape. The drug is only applied to the microneedle body, thus reducing costs. The microneedle patch is pressed on to the skin using the fingertips, and rapid drug release is achieved. Toxic side effects to the gastrointestinal tract are avoided, and bioavailability is improved. |