http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021138387-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e00f5cb90876276132c561a2b3e5c15 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10362 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10352 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
filingDate | 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f1f4e5980c47f11f32dd4087a68671c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4afb735c13139d3acdf71d1a0bdb02 |
publicationDate | 2021-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2021138387-A1 |
titleOfInvention | Culture systems for the efficient production of gene transfer vectors |
abstract | The production of gene transfer vectors that have been designed as replication deficient constructs can be inefficient, thus limiting their broad use in medicine. The present invention provides a solution to this problem. It describes how the production efficiencies can be enhanced for gene transfer vectors that are produced by the transfer of DNA and RNA into production cells. The present invention lies m the use of cell cycle control in optimizing the production of gene transfer vectors. The subject of this patent is the modification of cell growth and physiology to enhance the efficiency of vector production. An example is given for the effect of certain media components on the cell cycle and production rate of a fully deleted helper virus independent adenoviral vector. Other applications of this technology are listed. |
priorityDate | 2019-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 571.