http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021134135-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86e40de7b31f4c971a8c2b4f0aff3516 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36d9ae8e5ecf79711fc5fe8283798d6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_267e4265c652dcb9b944087f8e9d1b77 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F10-3286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F1-0054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54326 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_458be1242eed6b1966775db0a53a0e4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74471815445050c5b7bb689f1209a430 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_216da31ffcbac94bbbb2962b26cf12d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_545ba8b1e9f63d24b5f3930edc65722c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d12b7b07a5e1e476d814415f08376365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37089b01b6fac57d25d322ba130f8b66 |
| publicationDate | 2021-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021134135-A1 |
| titleOfInvention | System and method for detecting a biological analyte, including a microorganism, by a change in the magnetic property of a substrate, using superparamagnetic nanoparticles |
| abstract | The invention relates to a system comprising superparamagnetic or anhysteretic nanoparticles (NPs) functionalised with an antibody, and a thin-film-type substrate of metal or an oxide thereof, functionalised with the same antibody; and to a method for detecting a biological analyte, such as a cell, protein, microorganism or similar, preferably a pathogenic microorganism, and even more preferably Listeria. The method comprises: (a) obtaining a control signal from a substrate (magnetic or not) coated with a thin film of metal or an oxide thereof, preferably gold, which can be functionalised with an antibody, the control signal being a magnetoresistance signal, a total magnetisation signal or a signal of the magnetisation curve; (b) mixing superparamagnetic or anhysteretic NPs functionalised with the antibody, with a liquid sample to analyse and confirm the presence or absence of the biological analyte, the NPs and the liquid sample making contact for 10-90 minutes; (c) dripping the dispersion obtained in step (b) onto the substrate of step (a), and then washing to remove NPs that are not chemically anchored to the surface of the biological analyte; (d) leaving the substrate to dry and re-measuring a signal in the same way as carried out in step (a); and (e) counteracting the control signal obtained in step (a) and the signal obtained in step (d), and in the absence of differences between the two measurements, confirming the absence of the biological analyte in the sample, the amount of microorganisms being directly proportional to the signal measured. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113558597-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113558597-B |
| priorityDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.