| abstract |
The present invention relates to a preparation method for an injectable composition comprising a hyaluronic acid hydrogel and an anesthetic, and an injectable composition prepared thereby. The method comprises a step of washing and swelling a cross-linked hyaluronic acid hydrogel by means of a buffer solution comprising an anesthetic, thus allows the amount of various anesthetics such as lidocaine comprised in a finished preparation to be accurately adjusted, does not require a separate pH or osmotic pressure adjustment process, does not require a separate homogenizing process after the addition of the anesthetic, and allows easy management of processes. |