| abstract |
Provided are an acylsulfamide compound or a pharmaceutically acceptable salt thereof having NLRP3 inflammasome inhibitory activity, a pharmaceutical composition containing the same, a pharmaceutical use therefor, and the like. The acylsulfamide compound is the compound represented by formula (Ia) or a pharmaceutically acceptable salt thereof. (In the formula, the partial structure (AA) is formula (BB) or formula (CC), the ring Cy is a heteroaryl or a phenyl and may be substituted, and RDy and REy each independently represent hydrogen, a C1-6 alkyl that may be substituted, a C1-4 haloalkyl, a C3-6 cycloalkyl that may be substituted, a heterocycloalkyl that may be substituted, or a heteroaryl that may be substituted, or RDy and REy, which are bonded to a nitrogen atom, may form a heterocycloalkyl or the like together with the nitrogen atom.) |