http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021127565-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bd24d0edc441a277cf5d128b2c97b31 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-00 |
| filingDate | 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44751fce26f5a03201d99b781a52e6da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6ba5974e3b7c05a009efafddc54a439 |
| publicationDate | 2021-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021127565-A1 |
| titleOfInvention | Systems and methods for estimating cell source fractions using methylation information |
| abstract | A method of identifying a plurality of features for estimating subject cell source fraction is provided. For each respective training subject in a plurality of training subjects, a corresponding methylation pattern of each respective cell-free fragment in a corresponding training plurality of cell-free fragments and a corresponding subject cancer indication is obtained. Each cell-free fragment is mapped to a bin in a plurality of bins, each bin representing a portion of a human reference genome. A cell-free fragment cancer condition is assigned to each cell-free fragment, as a function of a classifier upon inputting a corresponding methylation pattern of the respective cell-free fragment into the classifier. A measure of association is determined for each bin between the subject cancer condition and the cell-free fragment cancer condition. The plurality of features for estimating subject cell source fraction are identified as a subset of the plurality of bins. |
| priorityDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.