abstract |
A process for continuous preparation of halogenated alkoxyethane of general formula XC1HC-CF 2 OR, where X is –Cl or –f and OR is C 1-4 alkoxy, the process comprising a step of introducing in a flow reactor reaction components comprising (i) a compound of general formula XC1HC-CYF 2 , where each of X and Y is independently –Cl or –F, (ii) a base, and (iii) a C 1-4 alkanol, wherein a) the flow reactor comprises one or more tubular flow line(s) through which the reaction components flow as a reaction mixture, c) the halogenated alkoxyethane is formed at least upon the reaction components mixing, with the so formed halogenated alkoxyethane flowing out of the flow reactor in a reactor effluent, and b) the base is one that forms a salt soluble in the alkanol during formation of the halogenated alkoxyethane. |