Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2271a966935737b6416b7614859d303 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-409 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409 |
filingDate |
2020-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88d04f17a4acc77a88f86125895136cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6825d57bd015d0e9b328eb5ced6e5c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9572949d0326bb40817217b82300ccc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff5cf5985d4db8dfb4f2e476e1cdd2f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0815ecfe10ad6d4a13ce0af0039d192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b8963fe4a3dfb8c21ee7c7c1f76e6d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ca9deebbb9c1604c63157eb3ff62f47 |
publicationDate |
2021-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021118298-A1 |
titleOfInvention |
Pharmaceutical composition, for preventing or treating fibrosis, comprising pheophorbide compound as active ingredient |
abstract |
The present invention relates to a pharmaceutical composition, for preventing or treating fibrosis, comprising a pheophorbide compound as an active ingredient. The present invention inhibits the activation and expression of collagen and fibronectin by inhibiting the signal transmission of TGF-β which is the cause of fibrosis, and thus can efficiently inhibit fiberization of tissues. The present invention also has notably superior anti-fibrotic activities over nintedanib or pirfenidone which are therapeutic agents for pulmonary fibrosis currently on the market, and thus will be widely used for preventing or treating fibrosis. |
priorityDate |
2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |