http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021116450-A1

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filingDate 2020-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7859c139e020bbcc1ea62c0316cb0c9c
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publicationDate 2021-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2021116450-A1
titleOfInvention System, method and sensor device for sensing a change in a concentration of micro-organisms
abstract A sensor device for use in sensing a change in a concentration of micro-organisms, comprises a waveguide interferometer having a sensing arm and a reference arm, a microfluidic channel for a fluid containing the micro-organisms, and a trapping arrangement in the microfluidic channel for physically trapping the micro-organisms when the fluid flows along the microfluidic channel so as to concentrate the micro-organisms in a sensing region of the microfluidic channel. The sensing arm is configured to guide sensing light, the reference arm is configured to guide reference light, and the waveguide interferometer is configured to interfere the sensing light with the reference light. The waveguide interferometer and the microfluidic channel are configured to allow the sensing light to interact with the fluid and the micro-organisms in the sensing region of the microfluidic channel. The sensor device may be used for sensing a change in a concentration of micro-organisms such as bacteria as a result of growth of the micro- organisms. The sensor device may be used for sensing the susceptibility of the growth of the micro-organisms to one or more micro-organism growth-inhibiting substances such as one or more antibiotics. The present disclosure also relates to a reader apparatus for reading the sensor device and an associated method.
priorityDate 2019-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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