abstract |
The invention relates to the field biopharmaceutics, and relates in particular to a pharmaceutical composition. The pharmaceutical composition contains a hepatitis B surface antigen, a hepatitis B core antigen and an immunostimulatory composition; the immunostimulatory composition contains saponins and CpG oligodeoxynucleotides, or consists of a saponin-containing adjuvant and CpG oligodeoxynucleotides. |