Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df2db1d44fb5ace39a3d80b4e3bd008d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c8f970e6c7f6df21b4665ddecc005ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3a3601621cc29a6f4645737c5477f7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d33e45e5cbd64b8b893bd62ee22a85b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 |
filingDate |
2020-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51890819f6ea738c705becb5665c2435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6633f617458d72a0137c3b50c2fa2c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f4daf55e02b4510994ad39ef8beb94b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f14bf1a100f21579bff2012f5704f8f5 |
publicationDate |
2021-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021105926-A2 |
titleOfInvention |
Mesenchymal stem cells with enhanced therapeutic properties |
abstract |
Mesenchymal stem cells with enhanced therapeutic properties. The present invention refers to a method for obtaining mesenchymal stem cells (MSCs) with enhanced immunosuppression, chondroprotection and chondrodifferentiation properties, and enhanced capability to promote the proliferation of chondrocytes. The method comprises contacting the MSCs; culturing MSC in a induction media supplemented with 0.01 to 100 µg/ml of an ATP-synthase inhibitor; and removing the induction media to obtain MSC with enhanced activity. Moreover, the present invention also refers to the MSCs themselves and to their use for cell therapy purposes, preferably for treating autoimmune and/or osteoarticular diseases. |
priorityDate |
2019-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |