abstract |
It is provided a cocrystal of a compound of formula (I) or of a compound formula (II) wherein X and Y are independently selected from -CH 2 - and -C(CH 2 )-, provided that al least one of X or Y is -CH 2 -; R 1 is -CHCH 3 -Z m -W n -(CH 2 ) o -T p -S, wherein Z is O, and m is 0 or 1; W is R 4 CH CHR 5 , wherein either R 4 and R 5 are H and the dashed line indicates that there is a single bond, or R 4 and R 5 together are forming a bond and the dashed line indicates that there is a double bond, and n is 0 or 1; o is 0, 1 or 3; T is selected from the group consisting of -CHR 6 -, -C(O), wherein R 6 is -OH or -CH 3 , and p is 0 or 1; S is selected from the group consisting of H, (C 1 -C 3 ) alkyl optionally substituted by -OH, (C 1 -C 3 ) haloalkyl optionally substituted by -OH, cyclopropyl, or; and R 2 is -H or -OH; R 3 is H or CH 3 ; and the dashed line in formula (II) indicates a single or a double bond; and a hydrogen bond donor coformer which is a phenolic compound. It is also provided a composition comprising the cocrystal and a personal care product comprising the composicion. |