http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021103816-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ba8bb65009910c3f6bfdd07c5fca155 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2509-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0682 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
filingDate | 2020-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7f0d6a1fc5b39ae719e38ef8f84972b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3a7a8c280e168fd478ee2cd52429afd |
publicationDate | 2021-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2021103816-A1 |
titleOfInvention | Use of uterine cavity fluid-derived exosome in preparation of therapeutic drugs and adjuvant therapeutic agents for treating infertility-related diseases |
abstract | Provided is use of a uterine cavity fluid-derived exosome in the preparation of therapeutic drugs and adjuvant therapeutic agents for treating infertility-related diseases. Experiments have demonstrated the exosome achieved the treatment or alleviation of endometrial aplastic diseases by promoting the increase of endometrial thickness, enhancing the viability of endometrial cells, reducing the damage to endometrial cells, promoting expression of VEGF, maintaining the stemness of endometrial stromal cells, and stimulating proliferation; the treatment or alleviation of a maternal-fetal immune tolerance disorder-related diseases is achieved by performing an immune tolerance effect, treating spontaneous abortion, and increasing the level of T-helper lymphocytes. In addition, the exosome can effectively increase the development rate of either fertilized eggs being fertilized in vivo or fertilized in vitro in a multiple manner, and improve the implantation rate and the farrowing rate of in vitro fertilization transplantation, having an auxiliary effect in the treatment of infertility. |
priorityDate | 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.