http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021096773-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3caf826151908460f17ec3d94f0698a6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1774 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 |
filingDate | 2020-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a45377c93312d7a9744bebc129b0ffd |
publicationDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2021096773-A1 |
titleOfInvention | A precision medicine method for immunotherapy |
abstract | Cancer immunotherapy has achieved immense clinical success with long survival even in the most difficult to treat cancer. Yet this effect is only observed in a minority and there are no biomarkers of this response. The methods described herein reduce immunosenescence, improve cancer immunotherapy outcomes, vaccination outcomes, and/or treatment of infectious diseases using two independent measures of systemic chronic inflammation (the inflammatory age -iAge- and cytokine response score - CRS) to stratify patients into responders versus non-responders to cancer immunotherapy, vaccination, and/or anti-pathogen therapies. The iAge personalized immune proteome signature creates an individualized initial therapy to reduce iAge and to convert nonresponders patients into responders prior to treatment. Nonresponders can be converted to responders by treating the patients to reduce their iAge and improve their CRS. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023027951-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115044552-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023038858-A1 |
priorityDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.