abstract |
To provide a method for production by direct transdifferentiation of a somatic cell into another somatic cell, the method being convenient and having good reproducibility and excellent production efficiency, and the method being performed in a short time. A method for production by direct transdifferentiation of a somatic cell into another somatic cell, the method being characterized by including: (a) a step for introducing a GLIS family gene, a mutant GLIS family gene, or a gene product thereof into a somatic cell; and (b) a step for culturing the transgenic somatic cell in a medium that contains a component for inducing differentiation from the somatic cell or a precursor cell of the somatic cell into another somatic cell. |