| abstract |
The compound represented by formula (I), and racemates, stereoisomers, tautomers, isotopic markers, nitrogen oxides, solvates, polymorphs, metabolites, esters, pharmaceutically acceptable salts, or prodrugs thereof. The compound represented by formula (I) has excellent ROCK inhibitory activity. In addition, the compound represented by formula (I) has good safety and metabolic stability. Furthermore, the compound represented by formula (I) has a low risk of potential hepatotoxicity. Finally, the compound represented by formula (I) has a simple preparation method and is easy to purify, and therefore has good application prospects. |