http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021091059-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_539523355646e5c74f4fe9985c1357bf |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-69 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
filingDate | 2020-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59720acfcca0aa324b2dce95c4a9cc59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81fa7fc1040b11a50cd5e71acda11876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c33bdbc2ad14937be38a37659f2a434 |
publicationDate | 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2021091059-A1 |
titleOfInvention | Inhibitor for carbapenem hydrolysis class d beta-lactamase (chdl) and preparation method thereof |
abstract | The present invention relates to an inhibitor for carbapenem hydrolysis class D beta-lactamase and a preparation method thereof and, more particularly, to [3-(2-phenylethoxy)phenyl]boronic acid or a pharmaceutically acceptable salt thereof for inhibiting CHDL, and a preparation method thereof. [3-(2-phenylethoxy)phenyl]boronic acid or a pharmaceutically acceptable salt thereof according to the present invention inhibits all six clinically important subgroups of CHDL and four newly emerging CHDL subgroups. Accordingly, the compound according to the present invention inhibits a wide variety of CHDLs such that when used together with beta-lactam antibiotics, the compound is effective for treatment of infections caused by bacteria that develop antibiotic resistance due to various CHDLs. |
priorityDate | 2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.