abstract |
Described herein are anti-angiopoictin-like 4 (ANGPTL4) antibodies and methods of treating disorders associated with elevated expression of ANGPTL4. In one aspect, described herein is an antibody or antigen binding fragment thereof that binds angiopoietin-like 4 (ANGPTL4) comprising amino acid sequences set forth in (a) SEQ ID NOs: 3-8 (Ab-A CDRs), (b) SEQ ID NOs: 13-18 (Ab-B CDRs), (c) SEQ ID NOs: 23-28 (Ab-C CDRs), (d) SEQ ID NOs: 33-38 (Ab-D CDRs), or (e) SEQ ID NOs: 43-48 (Ab-E CDRs). |