| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3511
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-902
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate |
2020-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffe6ce7e817278823b3a564c3780b1a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3d2ffa14cbc02f1064cbe7951e5b7df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3220c2ec4b51d8c3464632d7c16a32d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a66f98cc5b902270d6941fda6f7ea9a |
| publicationDate |
2021-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021081469-A2 |
| titleOfInvention |
Light-inducible crispr/cas9 system for genome editing |
| abstract |
A very fast and efficient CRISPR/Cas9 system is provided. Compositions include light-sensitive caged nucleotides at the PAM distal region of guide RNAs (gRNA caged ) to create artificial mismatches as a "roadblock". Upon light stimulation, the caging group ("roadblock") is removed and the gRNA fully hybridizes with the target DNA. Thus, the pre-bound inactive Cas9/gRNA caged is rapidly converted to active Cas9. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114703258-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114703258-B |
| priorityDate |
2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |