abstract |
The present invention relates to a topical pharmaceutical spray compositions comprising difluocortolone valerate, isoconazole nitrate, ethanol and propylene glycol, the process for preparing the compositions and uses thereof. The weight ratio of ethanol:propylene glycol is between 4,0:1 to 2,0:1 (w/w). More specifically, present invention relates to a topical pharmaceutical spray composition comprising 0,01 to 1,00 % by weight of difluocortolone valerate, 0,10 to 5,00 % by weight of isoconazole nitrate, 60,00 to 90,00 % by weight of ethanol 95 %, 8,00 to 40,00 % by weight of propylene glycol. |