http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021076918-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96411 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-918 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4727 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-563 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c2c06a30ffc93f46532a97ff2afcd4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5bc1be7fea9296b800685267b64a664 |
| publicationDate | 2021-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021076918-A1 |
| titleOfInvention | Assay for rapid evaluation of choroidal mast cell degranulation |
| abstract | The present invention relates to the field of ophthalmology. More specifically, the present invention provides compositions and methods useful for screening for drugs to treat age-related macular degeneration (AMD) including geographic atrophy (GA). In one embodiment, a method comprises the steps of (a) administering a drug to a mammal, wherein the mammal comprises a rat or a mouse; (b) enucleating the eyes of the mammal; (c) removing the anterior eye and excising the retina from the eye, wherein the eye comprises an eyecup that comprises choroidal mast cells (MCs); and (d) measuring mast cell degranulation. In an alternative embodiment, a method of the present invention can comprise the steps of (a) contacting an eyecup of a mammal with a drug, wherein the eyecup comprises choroidal mast cells; and (b) measuring MC degranulation. |
| priorityDate | 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 299.