| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8b06e78dc15cb7ec2b4e07ca61106d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3332c64284321d704b1a5a78742bfc7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate |
2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cace7d3606d4384bd0603b79ac29633
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f86da1657e96708ba646fbc2268681f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_272de0c395d2f2debb1dbf19a6d7cf25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6ebdabbe3fdbe7b95a7f2792567c691
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e190835922e821b7f9dcf86804ed6c2 |
| publicationDate |
2021-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021074391-A1 |
| titleOfInvention |
Methods for diagnosing nasal intestinal type adenocarcinomas |
| abstract |
The present invention relates to methods and compositions for the diagnostic and for the treatment of nasal intestinal type adenocarcinomas (ITAC). The inventors used a non-invasive brushing technique, which permits to identify transcriptomic and methylation modifications that are consistent with phenotypic profiles and ITACs natural history. Thus, they identified CACNA1C as a new predictive marker of ITAC. In particular, the invention relates to a method of determining whether a subject has or is at risk of having nasal intestinal type adenocarcinoma (ITAC) comprising determining the expression level of CACNA1C in a sample wherein said expression level indicates whether the subject has or is at risk of having a nasal intestinal type adenocarcinoma (ITAC). |
| priorityDate |
2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |