| abstract |
Provided is a method of treating a subject having a lysosomal storage disease, comprising administering red blood cells or Lin - hematopoietic stem and/or progenitor cells engineered to express a polypeptide, wherein the polypeptide can be α-GAL A or GRHPR. Also provided are a method of producing red blood cells from Lin - hematopoietic stem and/or progenitor cells in vitro, red blood cells produced by the method, and compositions comprising the red blood cells. |