http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021071334-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d4ad61d0af1fd483d31d1c5df9b9b76 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-328 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2020-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81f76a81b0635039d517e6cbb37affbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cd769d4ed659cf20cf67ad84b687a95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_076dba3046f9d8e04bddc4f9d98e43eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e95ee0dc7da04ff58ae9ae0bfc49f08d |
| publicationDate | 2021-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021071334-A1 |
| titleOfInvention | Pharmaceutical composition for preventing and treating type 2 diabetes, containing quercetin-3-o-xyloside |
| abstract | The present invention relates to a pharmaceutical composition for preventing and treating diabetes, containing quercetin-3-O-xyloside as an active ingredient. More specifically, the present invention demonstrates that: quercetin-3-O-xyloside reduces insulin resistance in insulin resistance induced myocytes, promotes glucose uptake and promotes the expression of GLUT-4, which is a glucose transporter membrane protein, and increases the rate of glucose uptake, thereby having antidiabetic effects; quercetin-3-O-xyloside inhibits α-glucosidase at least twice as effectively as acarbose, which is a current therapeutic agent for type 2 diabetes, thereby having excellent antidiabetic effects on type 2 diabetes; and, compared to a single substance of quercetin-3-O-xyloside, a 1:1 (mole : mole) complex of quercetin-3-O-xyloside and quercetin-3-O-rhamnoside has the synergistic effect of further increasing the rate of glucose uptake, thereby increasing antidiabetic effects. In addition, the present invention relates to a pharmaceutical composition for preventing and treating diabetes, containing the substance. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113440515-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113440515-B |
| priorityDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.