http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021064175-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec0024795f45a646ef64b3664ab8a26d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd7856a46a03951bbdaa4db9d494eaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_780c2144ff041130df005d95607da255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c77d687871ca59e1f543bb1170c208fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f74930f18c09888122c1ff39b35c028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0377ee49a719f8101e79984a05ac10d |
| publicationDate | 2021-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021064175-A1 |
| titleOfInvention | Compounds for preventing migration of cancer cells |
| abstract | The present invention relates to a composition for use in preventing migration of cancer cells in a subject known or suspected to suffer from cancer, the composition comprising at least one metal complex having the structure (I), formula (I), wherein M is a metal, preferably selected from the group consisting of copper, iron, manganese and zinc, X is Xa or Xb, wherein Xa is selected from the group consisting of O, S and -N(R1)-, wherein R1 is H or alkyl, and wherein Xb is a group forming a coordinate covalent bond to a second metal M', preferably a group O, S or -N(R1)-, wherein M' is preferably selected from the group consisting of copper, iron, manganese and zinc, and wherein M' and M may be the same or different and are preferably the same, Z1 and Z2, are independently of each other a, substituted or unsubstituted, -Aryl-O-, -Aryl-N- or heteroaryl group, Y is Ya or Yb, wherein Ya is selected from the group consisting of H, alkyl, -OH, -SH, halogen, and -NR3R4, wherein R3 and R4, are independently of each other selected from H and alkyl, preferably R3 and R4 are both H, and wherein Yb is a group forming a coordinate covalent bond to M or M', preferably Yb is a group O, S or -N(RYb1RYb2), wherein RYb1 and RYb1, are, independently of each other, H or alkyl, preferably H, and wherein n and m are integers, which are independently of each other, 0 or 1, Y2 is water or a halogen, and wherein Y3 is water or a halogen. The present invention further relates to a combined preparation comprising the aforesaid composition as well as to an in vitro method, for determining whether cancer cells are susceptible to immobilizing by the aforesaid compound. |
| priorityDate | 2019-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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