| abstract |
The invention relates to further medical uses of a polyglycerol derivative having a linear or dendritic polyglycerol backbone and carrying at least one thiol group covalently bound to the polyglycerol backbone, namely to its use as mucolytic; to its use in treating chronic sinusitis, asthma, chronic bronchitis, cystic fibrosis, chronic obstructive pulmonary disease, emphysema, or bronchiectasis; and to its use in treating chronic inflammatory bowel diseases, constipation, gastrointestinal malabsorption syndrome, irritable bowel syndrome, steatorrhea or diarrhea. The invention further relates to specific thiol-functionalized polyglycerol derivatives and to a corresponding manufacturing method. |