Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1117ec536a0d6b549bbf39148e7c1fa |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-115 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-741 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
filingDate |
2020-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d914aa45294b773dd2002dd02afa8dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b95aeece6e38fdf07d9341839f10edad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba36e0b201b4216b4977bef965a62e32 |
publicationDate |
2021-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021051095-A9 |
titleOfInvention |
Spore-based probiotic composition for modulation of microbiome in humans |
abstract |
A spore-based probiotic composition is provided that comprises at least one viable probiotic microorganism having a biological or therapeutic effect on microbiome in humans. One exemplary composition contains five different strains of Bacillus spp.. Also provided are methods of producing spore-based probiotic compositions. A validated in vitro gut model which is a simulated human intestinal microbial ecosystem reactor was used to assess the long-term effect of the composition on microbial metabolic activity and community composition. The results support use of the composition in protecting against obesity-related disorders, metabolic disorders, inflammation, and cancer, for example. A method for modulating microbial metabolic activity and/or modulating microbial community composition in a human subject is described. |
priorityDate |
2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |