http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021047212-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43e689f175057f56c04ebbccf59f8abe |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6417 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14fb548d1ea778e5ac67fc270df3139c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65d5043417eaa978b0a2075c148cecf4 |
| publicationDate | 2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021047212-A1 |
| titleOfInvention | Potassium ion fluorescent probe, preparation method and application thereof |
| abstract | The present application relates to a potassium ion fluorescent probe, a preparation method, and an application thereof. The potassium ion fluorescent probe has a structure represented by formula (I). The potassium ion fluorescent probe NK1 provided in the present application has short synthesis steps and a simple structure. Therein, ACLE is used as a K + recognition unit, a BODIPY derivative is used as a fluorophore, and TPP is used as the mitochondrial targeting group. Cooperation between these three enables the potassium ion fluorescent probe to have higher selectivity and sensitivity in the potassium ion identification process. The NK1 has few toxic side effects with respect to human cervical cancer cells (HeLa), high biocompatibility, and can also target mitochondria. Furthermore, the NK1 provided in the present application can qualitatively monitor the influx or outflow of potassium ions in cell mitochondria. |
| priorityDate | 2019-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.