http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021041469-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c8cbbf2290b3f3a9988da29598baa2c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H20-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 |
filingDate | 2020-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a54dc184bc900e000c0f0b3ad1f67e12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b709bc56ad3ea4851b8177e47d92e98 |
publicationDate | 2021-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2021041469-A1 |
titleOfInvention | Method and apparatus for individualized administration of medicaments for enhanced safe delivery within a therapeutic range |
abstract | Techniques for generating a dosing protocol for an individual include receiving first and second and third data. First data indicates, for dose response to a medicament, a continuous multivariate model with at least one distribution parameter characterizing variations in the population. Second data indicates a therapeutic range of values for the dose response. Third data indicates a cost function based on distance of a dose response from the therapeutic range. The method includes evaluating for a candidate dose an expected cost based at least in part on the distribution parameter and a Koopman transform of the cost function. When the expected cost is less than a threshold cost, the candidate dose of the medicament is administered to a subject. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020143924-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11728018-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2023268045-A1 |
priorityDate | 2019-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.