abstract |
A method for producing parvalbumin-positive nerve cells, said method comprising: an expression induction step for inducing the expression of Ascl1 gene, Dlx2 gene and MEF2C gene in cells; and a differentiation step for, after inducing the expression, culturing the cells and differentiating the cells into parvalbumin-positive nerve cells. A cell into which Ascl1 gene, Dlx2 gene and MEF2C gene have been introduced in an expressible manner. A differentiation inducer for inducing the differentiation of cells into parvalbumin-positive nerve cells, said differentiation inducer comprising, as an active ingredient, Ascl1 gene, Dlx2 gene and MEF2C gene or products of these genes. |