abstract |
The present invention relates (R)-9-(2,5-difluorophenethyl)-4-ethyl-2-methyl-1-oxa-4,9- diazaspiro[5.5]undecan-3-one, or a pharmaceutical acceptable salt thereof, for use in the treatment of nociceptive pain, neuropathic pain, osteoarthritis pain or cancer pain, while showing no tolerance after repeated administration and having reduced undesirable side effects as compared to strong opioids. |