| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bd24d0edc441a277cf5d128b2c97b31 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F30-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate |
2020-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_004133102f3a4dbfca3d4396287bb186
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44751fce26f5a03201d99b781a52e6da |
| publicationDate |
2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021016441-A1 |
| titleOfInvention |
Systems and methods for determining tumor fraction |
| abstract |
Systems and methods for determining a tumor fraction for a subject are provided. A plurality of bin values is obtained. Each respective bin value in the plurality of bin values corresponds to a bin in a plurality of bins. Each bin represents a corresponding region of a reference genome. The plurality of bin values is derived from a first biological sample of the subject. A plurality of copy number values is determined at least in part from the plurality of bins values. A plurality of allele frequencies for a plurality of alleles is derived from a second biological sample of the subject. At least the plurality of copy number values and the plurality of allele frequencies, or a plurality of features derived therefrom, are applied to a reference model, thereby determining the tumor fraction of the subject. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114970044-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114970044-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11530453-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11396679-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102491322-B1 |
| priorityDate |
2019-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |