| abstract |
Provided herein are methods for treating advanced relapsed solid tumors using 7- chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2, 4-dimethyl -N-((6-methyl-4-(methylthio)- 2-oxo-l,2-dihydropyridin-3-yl)methyl)benzo[d][l,3]dioxole-5-carboxamide; or a pharmaceutically acceptable salt thereof. Also provided herein are methods of treating cancers (e.g., solid tumors) using 7-chloro-2-(4-(3-methoxyazetidin-l-yl)cyclohexyl)-2,4- dimethyl-N-((6-methyl-4-(methylthio)-2-oxo-l,2-dihydropyri din-3- yl)methyl)benzo[d][1,3]dioxole-5-carboxamide; or a pharmaceutically acceptable salt thereof; and a second agent selected from a topoisomerase inhibitor, a DNA alkylating agent, and an androgen receptor signaling inhibitor. |