abstract |
Foam compositions that may be delivered to complex wound architecture, systems for delivering such foam compositions, and methods of use are described. The foam composition includes about 0.1 wt.% to about 45 wt.% collagen with a weight average molecular weight of about 5,000 to about 100,000; about 0.1 wt.% to about 45 wt.% oxidized regenerated cellulose (ORC); a total amount of about 0.001 wt.% to about 50 wt.% of one or more of a rheology modifier and a surfactant; about 50 wt.% to about 98 wt.% water; and a gas. In the foam composition, a weight ratio of collagen to ORC is about 90:10 to about 10:90 and the foam composition exhibits a foam capacity of about 20% to about 400%. |