Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6d40e044398947e5899630aa24f6402 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate |
2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29f6d20671831fad3e66fb646fdbd949 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62a4c8b4ad4a19ff234082f0d2ae507a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9612495d779246cc4f19ef42fff18c95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6afd244fadcfde3d9f003b74d77a2f4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dac99185f973ae20972c2ff33036b9f |
publicationDate |
2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021013078-A1 |
titleOfInvention |
Chimeric human papilloma virus 52 type l1 protein |
abstract |
A chimeric human papilloma virus (HPV) 52 type L1 protein and a polynucleotide encoding same, HPV 52 type virus-like particles and a preparation method therefor. The chimeric HPV 52 type L1 protein comprises: N-terminal fragments derived from the HPV 52 type L1 protein, the N-terminal fragments maintaining the immunogenicity of the HPV 52 type L1 protein; and C-terminal fragments derived from a second type papilloma virus L1 protein, the second type papilloma virus L1 protein having properties of higher L1 protein expression quantity and better solubility in comparison to any other type L1 protein. The chimeric HPV 52 type L1 protein has the immunogenicity of the HPV 52 type L1 protein. The chimeric HPV 52 type L1 protein has higher expression quantity and better solubility, and can be used for large scale production of vaccines. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113774071-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113774071-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022152204-A1 |
priorityDate |
2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |