Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cdd0ae33357cdb2d4daf56dee9ee32b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f764b5a908b0ae22b567769eb16d1b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a43e1cf3e83e27a1ce9f0fe61c83af46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c55693bb346ab742cba51bb4ef51d655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5375ab67dc29477f87bc1614b2d2fe4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 |
filingDate |
2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31209a0cf3fab3ad9f156df7d95432b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa68faa1e05ac01491a1624519d56943 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_195006d7804945e806eeeac089fabab5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5382179727f90697ea30f49ea6612601 |
publicationDate |
2021-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021009595-A1 |
titleOfInvention |
Cyclophosphamide injectable composition and methods for producing same |
abstract |
The present invention relates to stable injectable formulation comprising Cyclophosphamide as active ingredient and pharmaceutically acceptable excipients which is devoid of mannitol. The present invention also relates to methods for the preparation of pharmaceutical compositions of Cyclophosphamide by lyophilization process using solvent and optionally solubilizer wherein lyophilization process does not involve rehydration step. The present invention specifically relates to preparation of lyophilized pharmaceutical compositions of Cyclophosphamide with improved solubility and stability wherein the lyophilization process does not involve rehydration step and the composition is devoid of mannitol. The present invention specifically relates to preparation of stable injectable lyophilized formulation comprising Cyclophosphamide as active ingredient which is devoid of solubilizer as well as pharmaceutically acceptable excipients such as pH modifying agent and mannitol. |
priorityDate |
2019-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |