http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021005399-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c3d76288892ddbddca3e1fe2313ec5c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D7-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D7-329 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D7-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D7-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D7-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-34 |
| filingDate | 2019-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e379d7d4527600f81ca24d769141880a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbdb927b1a84e633091a013419f40b5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5073e37fa1e472f255e77c092b7002e |
| publicationDate | 2021-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2021005399-A1 |
| titleOfInvention | Compositions and methods for clearing tissue |
| abstract | Fine tissue structures, such as those in non-neural, non-osseous tissues or organs, is best performed in intact tissue. Compositions and methods for clearing tissues for subsequent three-dimensional analysis are described. The compositions as tissue clearing compositions are composed of four core components: (I) a homogenizing agent such as N-methylglucamine, urea, thiourea, guanidine, guanidinium chloride, lithium perchlorate, ethylenediamine, and derivatives thereof; (2) a water-soluble adjusting agent such as iohexol, sodium thiosulfate, polyethylene glycol, and derivatives thereof; (3) a lipid-soluble adjusting agent such as 2,2'-thiodiethanol, propylene glycol, and derivatives thereof; and (4) a borate compound such as boric acid, tetraboric acid, disodium tetraborate, and derivatives thereof. The discolsed tissue clearing compositions are particularly suitable for use with non-neural, non-osseous tissues or organs. The tissues or organs can be fresh, archived, or retrieved from paraffin wax-embedded tissues. |
| priorityDate | 2019-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.