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filingDate 2020-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020264186-A1
titleOfInvention Cells engineered for oligonucleotide delivery, and methods for making and using thereof
abstract The present disclosure is directed to genetically modified carrier/donor cells that are engineered to be resistant to its oligonucleotide payload, and methods of delivering an oligonucleotide into a target cell. The disclosure is also directed to methods of treating cancer using the engineered carrier cells of the disclosure. An aspect of this disclosure is directed to engineering carrier cells to be resistant to the detrimental effects of an oligonucleotide.
priorityDate 2019-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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