| abstract |
The present invention relates to methods for decreasing lipid production in sebocytes comprising the contacting of sebocytes with at least one triterpenoid compound, to compositions comprising at least one triterpenoid compound, to the use of such a composition for decreasing lipid production in sebocytes or for the manufacture of a pharmaceutical for decreasing lipid production in sebocytes, and to a cosmetic method for decreasing lipid production in sebocytes. In some embodiments, the triterpenoid compound of the herein described method is selected from the group consisting of hederagenin, ursonic acid, cycloastragenol, beta-elemonic acid, acetylursolic acid, alisol B 23-acetate, toosendanin, (20R)-protopanaxdiol, anemosapogenin, rutundic acid, and oleanolic acid. |