Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cf95d0896a674585abde2cf0e635333 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00117 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70578 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4727 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9b396ff827f19748f67304b0bea9fd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b5e2f2386df94e9854d7296341175e9 |
publicationDate |
2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020257191-A1 |
titleOfInvention |
Multimeric t-cell modulatory polypeptides and methods of use thereof |
abstract |
The present disclosure provides T-cell modulatory multimeric polypeptides that comprise an immunomodulatory polypeptide, a MUC1 epitope-presenting peptide, and class I MHC polypeptides. A T-cell modulatory multimeric polypeptide is useful for modulating the activit of a T cell, and for modulating an immune response in an individual. The present disclosure provides a T-cell modulatory multimeric polypeptide (TMMP) comprising: a) a first polypeptide; and b) a second polypeptide, wherein the TMMP comprises a MUC1 peptide; a first major histocompatibility complex (MHC) polypeptide; a second MHC polypeptide; one or more immunomodulatory polypeptides; and optionally an immunoglobulin (Ig) Fc polypeptide or a non-lg scaffold. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3897746-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11767355-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11739133-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11708400-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11702461-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11530248-B2 |
priorityDate |
2019-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |