http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020251645-A1

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filingDate 2020-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020251645-A1
titleOfInvention 7-gene prognostic and predictive assay for non-small cell lung cancer in formalin fixed and paraffin embedded samples
abstract A method of providing a treatment to a patient having non-small cell lung cancer is provided comprising extracting total RNA from a formalin fixed and paraffin embedded tumor of non-small cell lung cancer of a patient after the surgical resection, generating complementary DNA (cDNA) of the extracted total RNA from the patient's tumor, quantifying of mRNA expression of 7 genes of ABCC4 (SEQ ID NO:1), CCL19 (SEQ ID NO:2), SLC39A8 (SEQ ID NO:3), CD27 (SEQ ID NO:4), FUT7 (SEQ ID NO:5), ZNF71 (SEQ ID NO:6), and DAG1 (SEQ ID NO:7), normalizing of the quantification of the 7 genes with the quantification of a control gene UBC (SEQ ID NO:8) or a housekeeping gene, and utilizing the normalized 7 gene mRNA expression quantification to determine whether the patient will benefit from receiving adjuvant chemotherapy or not.
priorityDate 2018-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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