http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020249567-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_866607f8a0fc2069dbb5e04b4d027075 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0672 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-407 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
filingDate | 2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8663b1ae0b03cc2602e5b424563ebca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aae39b4930d6de125444338227c4af71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89b733d02e5b54bdb64be901939f23ff |
publicationDate | 2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2020249567-A1 |
titleOfInvention | Extracellular vesicles from human liver stem cells (hlsc-evs) for reducing cellular senescence |
abstract | There is disclosed a preparation of extracellular vesicles derived from human liver stem cells, preferably from a non-oval human progenitor cell line that expresses hepatic cell markers, which is capable of reducing the senescence of a population of senescent cells, as measured in a SA-ß-galactosidase-based cellular senescence assay. Also disclosed are therapeutic applications of the preparation of extracellular vesicles derived from human liver stem cells according to the invention. Therapeutic applications include the reduction of cellular senescence, e.g. in an vitro or ex vivo method, as well as the therapeutic treatment of diseases and conditions known to be related to ageing and cellular senescence, such as for example atherosclerosis, diabetes mellitus type 2, asthenia, and others. |
priorityDate | 2019-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 845.