| abstract |
The present invention, "a medicament for preventing and treating diabetes based on has-miR-320a, a screening method for the medicament, and a preparation method therefor," relates to the field of molecular medicine and the diagnosis, prevention, and treatment of metabolic diseases. The active ingredient of the medicament has has-miR-320a as the medicinal target and expresses the has-miR-320a by means of bonding, and/or capturing, and/or degrading, and/or reducing to provide the efficacy of diabetes prevention. The has-miR-320a is as represented by SEQ ID NO. 1. Moreover, also provided in the present invention are the screening method and the preparation method for the medicament. The employment of the medicament of the present invention significantly reduces the blood sugar concentration of a diabetic, effectively alleviates the symptoms of diabetes complications of a test animal, and allows the test animal to maintain healthy and stable blood sugar over a long time. |