http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020248359-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ee33b0e3e7398cf6fc957eeee59d510 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01212 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-77 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-15 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate | 2019-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_778567ab0b997ba60d0180a85084c7e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14290a3684eadfdfa937b9db51174bcc |
publicationDate | 2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2020248359-A1 |
titleOfInvention | Recombinant bacterium with high production of hyaluronic acid, construction method and application thereof |
abstract | The present invention relates to a recombinant bacterium with high production of hyaluronic acid, a construction method and an application thereof in the technical field of genetic engineering. The recombinant bacterium is constructed by enhancing the expression of the UDP-glucose dehydrogenase gene in the hyaluronic acid synthesis pathway while weakening the competitive pathway. The Corynebacterium glutamicum host is non-pathogenic to humans and animals and is a food-grade safe microorganism. The recombinant Corynebacterium glutamicum with high hyaluronic acid production has a high hyaluronic acid yield of up to 28 g/L or more, and has excellent prospects for industrial application. |
priorityDate | 2019-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 283.