| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7735054171fe6c74359414ade695f168
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2936d5500e94d1b421e3f068ba2dbef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63f2e75b4b2946a4386a52e8699f419f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1098
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-109 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82B3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-10 |
| filingDate |
2020-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9f40e0650d1b8806024d371cb6b8d5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_839b16fe59c8e04582af2823fdbc4c16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b0dafc61ec96caf62d30b27cf63a9e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84970c25cdd01e5cf07e9f09b0e85a52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_394a2215c90ad9eeb21e1074bed0e83c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_699ce70b467a927bc84ef7257acccef2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c6c91f1e89542ebce92b86efe06f465 |
| publicationDate |
2020-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020246913-A1 |
| titleOfInvention |
Method of producing a composition for boron neutron capture therapy of malignant tumors (embodiments) |
| abstract |
The group of inventions relates to the field of medicine, and specifically to methods of producing compositions for boron neutron capture therapy of malignant tumors, said compositions containing boron nanoparticles less than 100 nm in size, which methods are characterized in that a powder of elemental boron is sonicated in water for 0.5 to 800 minutes with an oscillation intensity of 1 to 1000 W/cm3 and an output power of more than 100 W, or is sonicated in water for 30 to 300 minutes with an oscillation intensity of 1 to 1000 W/cm3 and an output power of more than 100 W, then the upper portion of the composition with a volume of less than 50 vol% of the total volume of the composition is collected and said portion is sonicated with an oscillation intensity of 1 to 1000 W/cm3 and an output power of more than 100 W for 250-300 minutes. The group of inventions provides for the production of compositions for boron neutron capture therapy of malignant tumors with a high content of boron nanoparticles that are stable over time. |
| priorityDate |
2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |