| abstract |
The present invention relates to an oral preparation having an improved dissolution rate and disintegration properties for a natural substance extract, the oral preparation comprising poloxamer, as a solubilizer, and a water-insoluble diluent as main components in a processed ginseng extract, which is a representative natural substance extract, which contains increased amounts of ginsenoside Rg3 and Rh2 components which are trace amounts of ginsenoside components, and a configuration of additionally mixing-in a lubricant, a water-soluble diluent and a disintegrating agent has been confirmed, and in the oral preparation produced by said confirmed configuration, improvement in the dissolution rate and disintegration properties of the processed ginseng extract has been confirmed, and the maintaining of the improved dissolution rate and disintegration properties even during long-term storage has been confirmed, and thus the natural substance extract-containing preparation having an improved dissolution rate and disintegration properties of the present invention may be used to increase the bioavailability of the natural substance extract, and thus the preparation is expected to be usable for the development of an oral preparation having an increased physiological effect. |