| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1081 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 |
| filingDate |
2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c6fd22824738129616e6a98b5366fc7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30cdca080955341a6847223057ddc51c |
| publicationDate |
2020-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020245663-A1 |
| titleOfInvention |
Nanobody-based ns1 assay for the specific diagnosis of acute zika virus infection |
| abstract |
The invention described herein relates to single variable domain antibodies, heavy-chain antibodies and other polypeptides, kits, and compositions and methods of using the same in detection and diagnosis of ZIKA virus infection. In some embodiments, the invention provides the first antigen capture ELISA specific for ZIKV NS1 using VHH/nanobodies. In a particular embodiment, the invention provides anti-NSl VHH/nanobodies and a sandwich ELISA test that is performed, in one embodiment, by using an anti-NSl monoclonal antibody for the capture and ZIKV NS1 specific nanobodies of the invention for the detection step. This assay can be used with a broad range of cross-reactive anti-NSl MAb in combination with Zika-specific nanobodies such as those of the invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116063469-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116063469-A |
| priorityDate |
2019-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |