| abstract |
The present invention relates to a method of generating a hydrogel comprising alginate dialdehyde (ADA) and collagen, which are covalently cross-linked, and optionally, further component(s), and to uses of such hydrogel. The present invention further relates to using the hydrogel for culturing cells, in particular neuronal cells, and for further uses, such as 3D bioprinting. The present invention furthermore relates to a cell culture system comprising a hydrogel of alginate dialdehyde (ADA) and collagen, which are covalently cross-linked, and, optionally, further components. Furthermore, the present invention relates to a method of generating a three-dimensional (3D) cell culture using a hydrogel according to the invention. |