Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3127c0ebee3f865b211b019fac84286 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0635 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 |
filingDate |
2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797d5dd4fbeaa60581023fbad9a74e68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9422268be94051a036f7771d816b19bc |
publicationDate |
2020-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020243458-A1 |
titleOfInvention |
Therapeutic b-cells engineered to express bispecific t cell engager antibodies |
abstract |
Disclosed herein are therapeutic B lymphocytes engineered to express bispecific antibodies that are able to engage T-cells to destroy tumor cells. The B lymphocytes can be autologous, allogeneic, or syngeneic. Also disclosed is a pharmaceutical composition comprising a therapeutic B lymphocyte disclosed herein in a pharmaceutically acceptable carrier. Also disclosed herein is a method for treating cancer in a subject, comprising administering to the subject an effective amount of activated B lymphocytes engineered to express bispecific antibodies that are able to engage T-cells to destroy tumor cells. |
priorityDate |
2019-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |